Abstract #0615

Layer dependent changes of neural activity underlying laminar fMRI

Daniel Zaldivar¹, Yvette Bohraus², Nikos Logothetis^2,3,4, and Jozien Goense^5,6,7

¹LN, National Institute of Mental Health, Bethesda, MD, United States, ²Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, ³University of Manchester, Manchester, United Kingdom, ⁴International Center for Primate Brain Research, Shanghai, China, ⁵Department of Psychology, University of Illinois at Urbana-Champaign, Champaign, IL, United States, ⁶Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, ⁷Beckman Institute for Advanced Science and Technology, Urbana, IL, United States

Synopsis

Keywords: Brain Connectivity, fMRI, Laminar fMRI and neurophysiologyHow accurately fMRI reflects the underlying laminar differences in neural processing? In the current study we investigated the relationship between neural activity and fMRI signals across different cortical layers. We found layer and frequency dependent differences in neural activity during the presentation of visual stimulus that elicits positive and negative BOLD response.

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