Abstract #0628

Non-Contrast MRI of Micro-Vascularity of the Feet and Toes

Won Bae^1,2, Vadim Malis¹, Asako Yamamoto³, Yoshimori Kassai⁴, Jun Isogai⁵, Katsumi Nakamura⁶, John Lane⁷, and Mitsue Miyazaki¹

¹Radiology, University of California, San Diego, La Jolla, CA, United States, ²VA San Diego Healthcare System, San Diego, CA, United States, ³Radiology, Teikyo University, Tokyo, Japan, ⁴Canon Medical Systems Corp, Otawara, Japan, ⁵Radiology, Asahi General Hospital, Chiba, Japan, ⁶Kyoritsu Tobata Hospital, Kitakyusyu, Japan, ⁷University of California, San Diego, La Jolla, CA, United States

Synopsis

Keywords: MSK, Arterial spin labelling, Bilateral feet perfusion, ASL, Feet and ToesNon-contrast MR perfusion techniques were developed to assess micro-vascularity of the foot in humans. Using flow-out spin labeling with 3D SSFSE acquisition at multiple Tis, we obtained perfusion signal into distal feet and toes. Signal vs. TI data was fit to determine perfusion metrics including peak height (PH), apparent blood volume (aBV) and apparent blood flow (aBF). Compared to 1-tag, when 4-tag pulses were used PH, aBV, and aBF were significantly greater, suggesting increased signal afforded by the 4-tag pulses. This will be useful for subjects with low blood flow, such as those with peripheral artery disease.

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