Abstract #0673

Influence of gadolinium, field-strength and sequence on quantified perfusion values in phase-resolved functional lung MRI

Julian Glandorf^1,2, Fynn Brunzema^1,2, Filip Klimes^1,2, Lea Behrendt^1,2, Andreas Voskrebenzev^1,2, Marcel Gutberlet^1,2, Robert Grimm³, Frank Wacker^1,2, and Jens Vogel-Claussen^1,2

¹Institute for Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, ²Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Centre for Lung Research (DZL), Hannover, Germany, ³MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Synopsis

Keywords: Quantitative Imaging, Perfusion, LungThe aim of this study is the evaluation of the influences of previously applied gadolinium-based contrast media, differing field strength and differing imaging sequence on the lately proposed perfusion quantification for PREFUL MRI. The results indicate severe alterations and distortions of the quantified perfusion parameters after gadolinium administration and depending on the field strength and on the applied sequence type. The results show, that future multicenter studies need to strictly adhere to an identical imaging protocol using the same field strengths to generate comparable results across all sites.

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