Keywords: Stroke, Diffusion/other diffusion imaging techniques
The ischemic stroke cascade is a complex menagerie of processes causing disruption of neuronal function and willful and/or reactive breakdown of the neural vascular unit (NVU), and, prevails to recovery, repair, or patient demise. To better understand the underpinnings of the stroke cascade we applied our Multimodal Apparent Diffusion (MAD) method to multi b‑value diffusion weighted magnetic resonance imaging, up to b‑value of 10K s/mm2, on 41 consecutive stroke patients. Using Fuzzy C Means we were able to discern 13 normal appearing tissue types and 16 lesion types. There are several findings that should be contemplated in current clinical imaging.
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