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Abstract #0710

Self-supervised Learning with Self-supervised Regularization Reconstruction for Accelerated Single- and Multiband Myocardial Perfusion MRI

Changyu Sun1,2, Kenneth Bilchick3, Michael Salerno4, and Talissa A. Altes2
1Biomedical, Biological and Chemical Engineering, University of Missouri Columbia, Columbia, MO, United States, 2Radiology, University of Missouri Columbia, Columbia, MO, United States, 3Department of Medicine, University of Virginia Health System, Charlottesville, VA, United States, 4Department of Medicine, Stanford University, Stanford, CA, United States

Synopsis

Keywords: Image Reconstruction, Heart, Self-supervised LearningPhysics-guided self-supervised learning (PG-SSL) of MRI reconstruction may provide high spatiotemporal fidelity and fast reconstruction of highly accelerated first-pass myocardial perfusion MRI without ground truth. We sought to develop a SSL model with self-supervised regularization (SSR) using Siamese architecture with stop gradient and re-undersampling block to generate physics-based data augmentation and regularization. PG unrolled network was used as the sub-network in Siamese structure. Self-supervised learning with self-supervised regularization (SSLR) outperformed low rank plus sparse on retrospective rate-8 undersampling single-band data and showed improved SNR and temporal fidelity on prospective multiband whole-heart coverage high resolution perfusion imaging.

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