Abstract #0722

Value of diffusion kurtosis MR imaging for evaluating response to first-line chemotherapy in unresectable pancreatic cancer

Zehua Zhang¹, Caixia Fu², Robert Grimm³, and Zhengrong Zhou¹

¹Shanghai Cancer Center, Shanghai, China, ²MR Application Development, Siemens Shenzhen Magnetic Resonance Ltd, Shenzhen, China, ³MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany

Synopsis

Keywords: Pancreas, Diffusion/other diffusion imaging techniquesThis study firstly compared diffusion kurtosis imaging (DKI) and traditional diffusion weighted imaging (DWI) in evaluating first-line chemotherapy in unresectable pancreatic cancer. The result demonstrated that higher efficacy was shown in DKI derived parameters than DWI by the ROC curve analysis. DKI has potential to become a new non-invasive tool for clinical efficacy evaluation and help clinicians select individualized treatment.

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