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Abstract #0731

Value of multiple mathematical models of advanced zoomed DWI for the evaluation of tumor-stroma ratio in rectal cancer

Lijuan Wan1, Hongmei Zhang1, Yumeng Zhu2, Yueluan Jiang3, and Guang Yang4
1National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 2Beijing No.4 High School International Campus, Beijing, China, 3MR Scientific Marketing, Siemens Healthineers Ltd., Beijing, China, 4Shanghai Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai, China

Synopsis

Keywords: Pelvis, Cancer, Tumor microenvironmentTumor-stroma ratio (TSR) can reflect the relationship between tumor cells and tumor microenvironment. Evaluation of the TSR timely and accurately is important because of its role in predicting prognosis and making individualized treatment plans. Diffusion parameters obtained from multiple mathematical models of DWI can reflect microscopic characteristics of tumors. Multi b-value DWI with the advanced zoomed DWI technology can provide a higher-spatial-resolution with less artifacts. This study aimed to investigate the value of zoomed multi b-value DWI for predicting TSR in rectal cancer. The results suggested that distributed diffusion coefficient (DDC) is a promising indicator to identify high TSR group.

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