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Abstract #0758

Transmission of Rotary Excitation enables Quantification of Oscillating nT-Fields using a Linear Calibration Model

Petra Albertova1,2, Maximilian Gram1,2, Verena Schirmer2, Martin Blaimer3, Martin J. Herrmann4, Matthias Gamer5, Peter Nordbeck1,6, and Peter Michael Jakob2
1Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, 2Experimental Physics 5, University of Würzburg, Würzburg, Germany, 3Fraunhofer Institute for Integrated Circuits IIS, Würzburg, Germany, 4Department of Psychiatry, Psychosomatics, and Psychotherapy, University Hospital Würzburg, Würzburg, Germany, 5Department of Psychology, University of Würzburg, Würzburg, Germany, 6Comprehensive Heart Failure Center (CHFC), University Hospital Würzburg, Würzburg, Germany

Synopsis

Keywords: Bioeffects & Magnetic Fields, Quantitative Imaging, spin-lockRotary excitation based MRI, which enables spatially resolved, non-invasive, direct detection of biomagnetic fields, complements the measurement range accessible via MEG since detection is independent of the distance to the body surface. We present an extension of the REX method towards quantitative imaging. A calibration function can be composed from REX data of two measurements of adjustable fields projected onto the tissue by the scanner’s gradient system. In subsequent measurements, the field strength can be inferred from the calibration model. First in vivo proof-of-concept measurements show that the calibration successfully eliminates influences of tissue properties and accurately quantifies oscillatory nT-fields.

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