Keywords: Signal Modeling, Diffusion/other diffusion imaging techniquesThis study models the echo time (TE) dependence of the apparent soma and neurite signal fractions derived from the soma and neurite density imaging (SANDI) and quantifies the apparent compartmental T2 relaxation times in the grey matter (GM). The SANDI model divides the intra-cellular space into intra-neurite and intra-soma compartments to account for contribution of water diffusion in cell bodies. By collecting multi-TE SANDI datasets, we provide the first ever estimates of apparent intra-neurite and intra-soma T2 relaxation times in the human brain and characterise their distribution in cortical and subcortical GM regions.
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