Abstract #0775

BB MRI for monitoring aneurysm treatment – a novel biomarker?

Mariya S. Pravdivtseva¹, Hivnu Toraman², Jana Korte³, Franziska Gaidzik³, Philipp Berg³, Lana Bautz¹, Fritz Wodarg², Jan-Bernd Hövener¹, Olav Jansen², and Naomi Larsen²

¹Department of Radiology and Neuroradiology, Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany, Kiel, Germany, ²Department of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein (UKSH), Kiel University, Kiel, Germany, Kiel, Germany, ³Research Campus STIMULATE, University of Magdeburg, Magdeburg, Germany, Magdeburg, Germany

Synopsis

Keywords: Blood vessels, Phantoms, blood vessels, aneurysms, diagnostics, treatment evaluationTreating life-threatening intracranial aneurysms with flow modulating devices (FMDs) is mostly successfull, but may lead to complications and even delayed aneurysm rupture. A biomarker indicating treatment success is direly needed. Flow MRI can detect flow reduction, but it is impaired by metal artifacts from FMDs. Black-blood (BB) MRI is less sensitive to metal artifacts and often results in poor slow-flow suppression. We hypothesize that BB contrast changes after aneurysm treatment. Here, after placing FMDs in 3D-printed aneurysm models, an enhanced signal was found on BB MRI, associated with the reduced aneurysmal flow after flow modulation and thus possible treatment success.

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