Abstract #0783

Super-resolution assessment of relative pressure in intracranial atherosclerosis using ML-enhanced 4D Flow MRI

Patrick Winter^1,2, David Marlevi^3,4, Maria Aristova², Edward Ferdian⁵, Jonas Schollenberger⁶, Alireza Vali², Jackson Moore², Michael Markl², Ramez Abdallah², Sameer Ansari², C Alberto Figuerora⁶, David Nordsletten⁶, Alistair Young⁶, and Susanne Schnell^1,2

¹Department of Medical Physics, University of Greifswald, Greifswald, Germany, ²Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, ³Dept Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden, ⁴Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁵5Department of Anatomy and Medical Imaging, University of Auckland, Auckland, New Zealand, ⁶Department of Anatomy and Medical Imaging, University of Michigan, Ann Arbor, MI, United States

Synopsis

Keywords: Stroke, Atherosclerosis, intracranial atherosclerotic disease, stenosis, pressure differencesIn vivo measurements of intracranial pressure differences using 4D flow are useful to assess health risks associated with intracranial atherosclerotic disease (ICAD). In the clinical routine, approximations of the Navier-Stokes equation are used to derive relative pressure values, which can be inaccurate in intracranial vessels. Recently we presented an algorithm using a virtual work-energy formulation(vWERP). While this technique yields more accurate pressure estimations in intracranial settings, still systematic errors due to insufficient spatial resolution were observed. Here, we apply artificial intelligence-based super resolution for more accurate assessments of pressure values near the stenosis in a cohort of ICAD patients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.