Keywords: Liver, Cancer, HCCThis study assessed the imaging outcomes of Liver Imaging Reporting and Data System (LI-RADS) v2018 category 2, 3, and 4 observations in prospective hepatocellular carcinoma (HCC) surveillance cohort. LI-RADS observations demonstrate increasing risk of progression to HCC with increasing category. About two-fifths of LR-4 progressed to a malignant category. LR-3 observations with APHE or threshold/subthreshold growth upgraded to LR-5 were significantly higher. Most LR-2 observations that remain stable in category for at least two years.
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