Abstract #0801

Differentiating Benign from Malignant Gallbladder Wall Thickening in Non-Contrast MRI Imaging: Preliminary Study of a Combined Indicator

Wen-Wen He¹, Hai-Ge Li¹, Jian-Guo Zhu¹, Dmytro Pylypenko², Fei Liu¹, Mei Wang¹, Yue-Fei Wu³, and Jun Tian³

¹Radiology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China, ²GE Healthcare, China, Beijing, Beijing, China, ³The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China

Synopsis

Keywords: Cancer, BiliaryThis study evaluated the diagnostic accuracy of image features for differentiating benign from malignant gallbladder wall thickening disease with non-contrast MRI and constructed the optimal diagnostic indicator. 23 patients with wall thickening type gallbladder carcinoma and 61 patients with benign wall thickening disease were included. Six image indicators (the layered pattern on T2WI and DWI images, T2WI signal intensity, papillary growth, ADC value, and ratio of the ADC value of the lesion to that of liver parenchyma) were shown to have high diagnostic accuracy. The layered pattern on DWI combined with papillary growth was demonstrated as the optimal indicator.

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