Keywords: Hyperpolarized MR (Gas), SpectroscopyHyperpolarized 129Xe gas exchange MR spectra exhibit cardiogenic oscillations that have been found to distinguish between groups of cardiopulmonary diseases. Specifically, oscillations in the amplitude of the 129Xe red blood cell (RBC) resonance can differentiate pre-capillary and post-capillary pulmonary hypertension. Before diagnostic relevance can be established, these oscillations must be robustly quantified and definitive reference values must be determined. Here, we compare oscillation quantification using a constrained peak-finding algorithm against results from conventional sine fitting. We then employ a well-curated healthy cohort to establish reference values for cardiogenic oscillations in 129Xe RBC spectral parameters, using both methods.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords