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Abstract #0886

The validation of ASL-aCBV measured by Hadamard encoded ASL imaging evaluating moyamoya disease correlative study with 15O-H2O PET-aCBV.

Hirohiko Kimura1,2, Makoto Isozaki3, Shota Ishida4, Naoyuki Takei5, Yasuhiro Fujiwara6, Yuki Matta7, HIdehikko Okazawa8, and Tetsuya Tsujikawa9
1Faculty of Medical Sciences, University of Fukui, Eiheiji, Japan, 2Radiology, National Health Insurance Echizen-cho Ota Hospital, Fukui, Japan, 3Neurosurgery, University of Fukui, Eiheiji, Japan, 4Department of Radiological Technolog, Kyoto College of Medical Science, Kyoto, Japan, 5GE Healthcare, Hino, Japan, 6Kumamoto University, Kumamoto, Japan, 7University of Fukui Hospital, Eiheiji, Japan, 8Biomedical Imaging Research Center, University of Fukui, Eiheiji, Japan, 9Department of Radiology, University of Fukui, Eiheiji, Japan

Synopsis

Keywords: Stroke, Perfusion, Arterial spin labeling, CBF, CBVPositron emission computed tomography (PET) has been used for evaluating cerebral blood flow (CBF) in moyamoya disease to diagnose and assess revascularization result for the patient. Using Hadamard encoded method and DANTE vascular suppression, arterial transit time (ATT) and delay corrected both CBF and aCBV could be obtained in clinical setting. This study aimed to clarify whether ASL- aCBV hemodynamically related to PET-V0 obtained from PET data. There was a significant correlation between PET and CBF both on CBF and aCBV. This may suggest that aCBV could become an additional hemodynamic parameter related to aCBV in completely non-invasive way.

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