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Abstract #0891

Anatomical MRI-guided deep learning-based low-count PET image recovery without the need for training data – a PET/MR study

Tianyun Zhao1, Thomas Hagan1, Christine DeLorenzo1,2, and Chuan Huang1,3
1Biomedical Engineering, Stony Brook University, Stony Brook, NY, United States, 2Psychiatry, Stony Brook Medicine, Stony Brook, NY, United States, 3Radiology, Stony Brook Medicine, Stony Brook, NY, United States

Synopsis

Keywords: PET/MR, PET/MR

The advent of simultaneous PET/MRI enables the possibility of using MRI to guide PET image reconstruction/recovery. Deep-learning approaches have been explored in low-count PET recovery, with current approaches focus on supervised learning, which requires a large amount of training data. A recently proposed unsupervised learning image-recovery approach does not require this but relies on the optimal stopping criterion. In this work, we developed an unsupervised learning-based PET image recovery approach using anatomical MRI as input and a novel stopping criterion. Our method achieved better image recovery in both global image similarity metrics and regional standard uptake value (SUV) accuracy.

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Keywords