Abstract #0909

Can APT-weighted CEST MRI provide robust measurement at 3T? A reproducibility study in healthy brain and tumor across sessions and scanners

Yulun Wu^1,2, Tobias C. Wood³, Sophie H.A.E. Derks^1,4, Ilanah J. Pruis¹, Sebastian van der Voort^1,5, Sophie E.M. Veldhuijzen van Zanten¹, Marion Smits^1,2,5, and Esther A.H. Warnert^1,2

¹Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, Netherlands, ²Brain Tumour Centre, Erasmus MC Cancer Institute, Rotterdam, Netherlands, ³Centre for Neuroimaging Science, King's College London, London, United Kingdom, ⁴Department of Medical Oncology, Erasmus MC, Rotterdam, Netherlands, ⁵Medical Delta, Delft, Netherlands

Synopsis

Keywords: CEST & MT, CEST & MT, Amide, reproducibility, brain tumorThe goal of this study was to investigate whether APT-weighted CEST imaging can provide reproducible measurements across scan sessions and scanners. Reproducibility of APT-weighted imaging in healthy brain tissue and tumors was evaluated for three CEST metrics: Lorentzian Difference (LD), magnetization transfer ratio asymmetry (MTR_asym), and relaxation-compensated inverse magnetization transfer ratio (MTR_REX).

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.