Abstract #0915

Observing visually evoked responses in human thalamus and cortex at millisecond temporal resolution: Preliminary study at 3 T

Phan Tan Toi^1,2, Sehong Oh³, and Jang-Yeon Park^1,2

¹Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, ²Department of Intelligent Precision Healthcare Convergence, Sungkyunkwan University, Suwon, Korea, Republic of, ³Division of Biomedical Engineering, Hankuk University of Foreign Studies, Yongin, Korea, Republic of

Synopsis

Keywords: fMRI, BrainThere has been interested in observing neural activity dynamics in humans at high temporospatial resolution using noninvasive neuroimaging. Here, we report preliminary results of direct imaging of neuronal activity (DIANA) in humans at 3T using checkerboard pattern stimulation. The results show sequential temporospatial dynamics of activities in visual and prefrontal areas evoked by checkerboard pattern stimulation with a signal change of 0.1~0.3%. In contrast, DIANA signals were distinct from control experiments compared with checkerboard pattern stimulation ones. Our preliminary observations suggest that DIANA is feasible for human fMRI studies.

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