Abstract #0924
4D flow MRI to evaluate flow and future liver remnant growth after portal vein embolization
Thekla Helene Oechtering1,2, Tilman Schubert1,3, Qianqian Zhao4, Roxana A Alexandridis4, Nikolaos Panagiotopoulos1,2, Oliver Wieben1,5, Kevin M Johnson1,6, Alejandro Roldán-Alzate7,8,9, and Scott B Reeder1,5,8,9,10
1Department of Radiology, University of Wisconsin-Madison, Madison, USA, WI, United States, 2Department of Radiology, Universität zu Lübeck, Lübeck, Germany, 3Department of Neuroradiology, Zurich University Hospital, Zurich, Switzerland, 4Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, United States, 5Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 6Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI, United States, 7Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, 8Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 9Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 10Department of Emergency Medicine, University of Wisconsin-Madison, Madison, WI, United States
Synopsis
Keywords: Liver, Velocity & Flow
Early prediction of remnant liver growth after portal vein embolization (PVE) would enable earlier surgery in patients with liver malignancies and thus decrease the risk of tumor progression. Portal blood flow after PVE holds the potential to be an important predictor for hypertrophy of the non-embolized segments. We demonstrated the feasibility of 4D flow MRI quantification of portal blood flow before and after PVE in a porcine model. Flow changes immediately after PVE were predictive of the change in liver volume 2 weeks post PVE in both the embolized and non-embolized liver lobes.
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