Abstract #0930

2.5D Flow MRI: 2D phase-contrast of the tricuspid valvular flow with automated valve-tracking

Jerome Lamy¹, Jie Xiang¹, Felicia Seemann², Ricardo A Gonzales³, Steffen Huber¹, Jeremy Steele⁴, Einar Heiberg⁵, and Dana C Peters¹

¹Radiology and Biomedical Imaging, Yale University, New Haven, CT, United States, ²National Institutes of Health, Bethesda, MD, United States, ³Oxford University, Oxford, United Kingdom, ⁴Internal Medicine, Yale University, New Haven, CT, United States, ⁵Lund University, Lund, Sweden

Synopsis

Keywords: Flow, Data AcquisitionTricuspid regurgitant velocity is a crucial biomarker in identifying pressure overload in the right heart, associated with diastolic dysfunction and pulmonary hypertension. 2D phase-contrast cannot quantify this flow, and echocardiography is used clinically. We developed a phase-contrast method which utilizes deep-learning algorithms to track the valvular slice in a cardiac phase-dependent manner, which we call 2.5D flow. We studied its performance in nine healthy subjects and patients with tricuspid regurgitation. RV stroke volumes correlated better to forward flow volumes by 2.5D flow vs. static 2D phase-contrast (ICC=0.88 vs. 0.62). 2.5D flow characterized regurgitation in a patient.

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