Keywords: Data Acquisition, Multimodal, Polarized Light Imaging, Optics, FerretThis study uses complete polarimetry to capture diattenuation and retardance in post-mortem ferret optic chiasm (OC) chosen for its well understood fiber structure. These methods are novel due to the limited analysis of diattenuation metrics on tissue. Our results suggest that retardance measurements are sensitive to microscale features rather than to macroscale geometry when compared to fractional anisotropy (FA) and propagator anisotropy (PA). In addition, we have shown fiber orientation distributions (FODs) created through direct optical measurement of the tissue on a 2D plane are comparable to diffusion FODs.
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