Abstract #0996

A first application of the ILAE consensus protocol for 7T epilepsy imaging in addition to clinical practice

Gilbert Hangel^1,2,3, Gregor Kasprian⁴, Stefanie Chambers^1,2, Lukas Haider⁴, Philipp Lazen^1,2, Johannes Koren⁵, Robert Diehm⁶, Katharina Moser⁶, Matthias Tomschik¹, Jonathan Wais¹, Fabian Winter¹, Vitalij Zeiser¹, Stephan Gruber², Susanne Aull-Watschinger⁷, Tatjana Traub-Weidinger⁸, Christoph Baumgartner⁵, Martha Feucht⁶, Christian Dorfer¹, Wolfgang Bogner², Siegfried Trattnig², Ekaterina Pataraia⁷, and Karl Rössler¹

¹Department of Neurosurgery, Medical University of Vienna, Vienna, Austria, ²High-field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ³Christian Doppler Laboratory for MR Imaging Biomarkers, Vienna, Austria, ⁴Division of Neuroradiology and Musculoskeletal Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ⁵Department of Neurology, Klinik Hietzing, Vienna, Austria, ⁶Center for Rare and Complex Childhood Onset Epilepsies, Member of ERN EpiCARE, Department of Pediatrics and, Medical University of Vienna, Vienna, Austria, ⁷Department of Neurology, Medical University of Vienna, Vienna, Austria, ⁸Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Wien, Austria

Synopsis

Keywords: Epilepsy, BrainIn a cohort of 38 patients with pharmacoresistant focal epilepsy, our implementation of the 2021 ILAE 7T consensus protocol found lesions in 19% of 3T MR-negative cases and improved delineation of lesions in 88% of 3T MR-positive cases, with statistically significant higher detection confidence at 7T. Our results conform to literature and show the surplus effect of the consensus protocol in addition to clinical standard diagnostics and point at a potential main use of better surgical planning in known lesions.

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