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Abstract #1023

MR SIGNATURE MATCHING (MRSIGMA) FOR VOLUMETRIC MRI WITH LESS THAN 300MS LATENCY ON A 1.5T MR-LINAC SYSTEM

Syed Saad Siddiq1, Victor Murray1, Neelam Tyagi1, Pim T.S. Borman2, Bas W. Raaymakers2, Can Wu1, and Ricardo Otazo1,3
1Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, United States, 2Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, 3Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States

Synopsis

Keywords: Hybrid & Novel Systems Technology, RadiotherapyThe MR-Linac system offers a platform to adapt and monitor radiotherapy of tumors affected by continuous motion in real-time. However, real-time MRI technology is restricted to 2D imaging, which limits performance. MR Signature Matching (MRSIGMA) is a recently developed real-time 3D MRI technique with the MR-Linac as a target. However, MRSIGMA was tested only in a non-real-time scenario. This work develops a real-time implementation of MRSIGMA on the Elekta Unity 1.5T MR-Linac, including raw data transmission to an external computer, deep learning 4D reconstruction and correlation-based matching to demonstrate total imaging latency lower than 300ms.

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