Abstract #1050

Imaging of Irradiation Effects in Brain Tissues by Electrical Conductivity Using MRI

Nitish Katoch¹, Bup Kyung Choi¹, Ji Ae Park², Tae Hoon Kim³, Young Hoe Hur⁴, Jin Woong Kim⁵, and Hyung Joong Kim¹

¹Department of Biomedical Engineering, Kyung Hee University, Seoul, Korea, Republic of, ²Division of Applied RI, Korea Institute of Radiological and Medical Science, Seoul, Korea, Republic of, ³Medical Convergence Research Center, Wonkwang University Hospital, Iksan, Korea, Republic of, ⁴Department of Hepato-Biliary-Pancreas Surgery, Chonnam National University Medical School, Gwangju, Korea, Republic of, ⁵Department of Radiology, Chosun University Hospital and Chosun University College of Medicine, Gwangju, Korea, Republic of

Synopsis

Keywords: Electromagnetic Tissue Properties, Electromagnetic Tissue Properties, Electrical Conductivity, MREPT, Radiation Therapy, High-field MRIRadiation-induced injury can damage normal tissues caused by unintentional exposure to ionizing radiation. Image-based evaluation of tissue damage by irradiation has an advantage for the early assessment of therapeutic effects. This study aims to non-invasively evaluate tissue response following radiation therapy in phantoms and in vivo mouse brains at 3T and 9.4T MRI scanner. Due to changes in ionic strength in tissue after radiation, magnetic resonance (MR)-based electrical properties tomography could be a suitable imaging tool to assess the radiation therapy response on biological tissues.

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