Keywords: Heart, PerfusionMyocardial perfusion can be quantitatively measured noninvasively using arterial spin labeling (ASL). Motion due to the cardiac cycle is tackled with the use of single- or double-ECG gating. The goals of this study were to investigate the performance of double-gating, in synchronized breathing myocardial ASL with presaturation pulses by comparison with single-gating, and to compare the different quantification strategies for double-gated data. This study showed that double-gating is more robust to heart rate variability than single-gating in synchronized breathing ASL sequences with presaturation pulses, but accurate saturation-recovery fitting requires the acquisition of several baseline images.
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