Abstract #1074

DIRECT: non-contrast-enhanced relaxation-based flow-independent intracranial MR angiography using modified REACT

Masami Yoneyama¹, Takayuki Sakai², Yasuhiro Goto³, Masanobu Nakamura¹, Daichi Murayama², Michinobu Nagao⁴, Shuo Zhang⁵, Kayoko Abe⁴, Yutaka Hamatani³, Kazuo Kodaira³, Takumi Ogawa³, Mana Kato³, Isao Shiina³, and Marc Van Cauteren⁶

¹Philips Japan, Tokyo, Japan, ²Department of Radiology, Eastern Chiba Medical Center, Chiba, Japan, ³Department of Radiological Services, Tokyo Women's Medical University, Tokyo, Japan, ⁴Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women’s Medical University, Tokyo, Japan, ⁵Philips Healthcare, Hamburg, Germany, ⁶Philips Healthcare, Best, Netherlands

Synopsis

Keywords: Vessels, Blood vesselsA new non-contrast-enhanced, relaxation-based, flow-independent MRA method, called Relaxation-Enhanced Angiography without ContrasT (REACT) has recently been proposed for vascular imaging. One of the major limitations of REACT is that bright signal of long-T1 fluids such as CSF is visible, which can obscure vascular structure in the intracranial vessels. We developed a new sequence, called DIRECT (Dual-Inversion REaCT) with modified magnetization preparation scheme of REACT to suppress CSF signals while maintain the high signal intensity from vessels. DIRECT enables robust and high-quality whole-brain intracranial MR angiography with uniform fat, CSF and brain parenchyma suppression within clinically feasible scan time.

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