Abstract #1082

Improved Simultaneous Intracranial Vessel Wall Imaging and dynamic MRA Using Low-rank Reconstruction

Kaiyu Zhang¹, Zhensen Chen², Yin Guo¹, Xin Wang³, Gador Canton⁴, Niranjan Balu⁴, Thomas Hatsukami⁵, Chun Yuan^4,6, and Xiaodong Ma⁶

¹Department of Bioengineering, University of Washington, Seattle, WA, United States, ²Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, ³Department of Electrical Engineering, University of Washington, Seattle, WA, United States, ⁴Department of Radiology, University of Washington, Seattle, WA, United States, ⁵Department of Surgery, University of Washington, Seattle, WA, United States, ⁶Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States

Synopsis

Keywords: Vessel Wall, Blood vesselsAcquiring multi-contrast images of intracranial vessels from one single MRI sequence is beneficial for comprehensive neurovascular disease diagnosis. Vessel wall (VW) images and dynamic MRA (dMRA) can be obtained from a time-efficient multi-contrast sequence named iSNAP. However, the previously adopted k-space sharing reconstruction method generated high-quality dMRA but low-quality VW images. In this study, we aim to develop a novel low-rank-based image reconstruction method to reconstruct VW and dMRA from highly undersampled 4D MRI. High quality VW images with sharper wall delineation are obtained, while hemodynamic information from dMRA is preserved.

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