Abstract #1093

Towards isotropic 3D whole-heart T1 mapping using model-based motion-corrected super-resolution reconstruction

Simone Hufnagel¹, Patrick Schuenke¹, Jeanette Schulz-Menger^2,3,4, Tobias Schaeffter^1,5,6, and Christoph Kolbitsch¹

¹Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany, ²Charité Medical Faculty University Medicine, Berlin, Germany, ³Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center (ECRC), Charité Humboldt University Berlin, DZHK partner site Berlin, Berlin, Germany, ⁴Department of Cardiology and Nephrology, HELIOS Klinikum Berlin Buch, Berlin, Germany, ⁵School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, ⁶Department of Biomedical Engineering, Technical University of Berlin, Berlin, Germany

Synopsis

Keywords: Quantitative Imaging, Heart, Super-Resolution Reconstruction

Cardiac T1 mapping provides valuable information for the diagnosis of a variety of heart diseases. However, due to SNR and scan time limitations, often only 2D imaging with a low through-plane resolution covering a few slices of the left ventricle is possible. In this work, a super-resolution reconstruction approach is presented aiming towards whole-heart 1.3 mm isotropic T1 mapping within less than three minutes acquisition time. The proposed approach provided a whole-heart cardiac T1 map including the atria and the right ventricle with improved visualization of small structures and overall image quality.

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