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Abstract #1100

Bayesian Networks Reveal the Interplay Between Quantitative Liver MRI Metrics

Yi-Chun Wang1,2, Roberto Salvati2, John Connell2, Natali Van Zijl1, Tom Waddell2, Daniel Bulte1, and Michael Brady2
1University of Oxford, Oxford, United Kingdom, 2Perspectum, Oxford, United Kingdom

Synopsis

Keywords: Quantitative Imaging, Liver, cT1, T2*, PDFF, volume, future liver remnantUnderstanding the interplay between quantitative MRI metrics is crucial for reliable clinical assessment of liver health. This study utilised Bayesian networks to visualise hidden relationships between cT1, T2*, proton density fat fraction (PDFF), volume and future liver remnant (FLR). Analysing the directionality between Bayesian networks on a pre-operative dataset with 130 participants and a post-operative dataset with 90 participants, clear causal relationships from PDFF to cT1 and from PDFF to volume were found, which are supported by published literature. An additional discovery is the potential for correlation between metrics to help strengthen the clinical utility of cT1 after surgery.

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Keywords