Meeting Banner
Abstract #1107

Validation of Constrained qBOLD-Based 3D CMRO2 Mapping With Repeatability Test and Hypercapnic Challenge

Hyunyeol Lee1,2, Jing Xu2, and Felix W Wehrli2
1School of Electronics Engineering, Kyungpook National University, Daegu, Korea, Republic of, 2Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States

Synopsis

Keywords: Quantitative Imaging, MetabolismIn the original qBOLD, it is challenging to separate deoxyhemoglobin’s contribution to R2' from other sources modulating the voxel signal. Further, extracting DBV and Yv from measured R2' is a nontrivial task. It was recently shown that the constrained qBOLD method was able to properly separate the several confounding factors, yielding the expected contrast for both Yv and DBV maps across the entire brain, and, together with a separate measurement of CBF, leading to whole-brain 3D CMRO2 maps within physiologically plausible ranges. Here, we validated the new 3D qBOLD method with respect to repeatability and hypercapnic gas breathing challenges.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords