Abstract #1109

Bariatric Surgery Effects on Knee Articular Cartilage and Osteoarthritis Symptoms – a 12-month Follow-up Using T2 Relaxation Time and WOMAC Index

Sami Lehtovirta^1,2, Ahti Kemppainen^1,2, Marianne Haapea^2,3,4, Jaro Karppinen^1,5,6, Eveliina Lammentausta^2,3, Vesa Koivukangas⁷, Eero Kyllönen⁸, Mika Nevalainen^1,2,3, Petri Lehenkari^2,7,9, Victor Casula^1,2, and Miika T. Nieminen^1,2,3

¹Research Unit of Health Science and Technology, University of Oulu, Oulu, Finland, ²Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland, ³Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, ⁴Research Service Unit, Oulu University Hospital, Oulu, Finland, ⁵Center for Life Course Health Research, University of Oulu, Oulu, Finland, ⁶Finnish Institute of Occupational Health, Oulu, Finland, ⁷Department of Surgery, Oulu University Hospital, Oulu, Finland, ⁸Department of Physical Medicine and Rehabilitation, Oulu University Hospital, Oulu, Finland, ⁹Research Unit of Translational Medicine, University of Oulu, Oulu, Finland

Synopsis

Keywords: Cartilage, OsteoarthritisObesity is a common risk factor for osteoarthritis (OA). We set out to study knee cartilage using T2 relaxation time, and knee OA symptoms with WOMAC OA index in obese individuals. Bariatric surgery patients were split into successful and unsuccessful weight loss groups, and compared with a control group of obese individuals over a 12-month follow-up. The lesser weight loss group displayed improvement of cartilage with lower T2 values in the lateral compartment of femoral cartilage, compared to the higher weight loss. We also observed improvement of knee symptoms in both successful and unsuccessful weight loss groups after 12 months.

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