Abstract #1111

High Contrast Cartilaginous Endplate Imaging Using Dual-Inversion Recovery Prepared Ultrashort Echo Time (DIR-UTE) Sequence

Jiyo Srinivasan Athertya¹, James Lo^1,2, Alicia Ji¹, Charles Ding¹, Xiaojun Chen¹, Soo Hyun Shin¹, Bhavsimran Singh Malhi ¹, Saeed Jerban¹, Micael Carl³, Monica Guma^4,5, Eric Y Chang^1,5, Jiang Du^1,2,5, and Yajun Ma¹

¹Radiology, UCSD, San Diego, CA, United States, ²Bioengineering, UCSD, San Diego, CA, United States, ³GE Healthcare, San Diego, CA, United States, ⁴Medicine, UCSD, San Diego, CA, United States, ⁵Radiology Service, VA, San Diego, CA, United States

Synopsis

Keywords: MSK, Contrast Mechanisms, Cartilaginous endplate, SpineThe cartilaginous endplate (CEP) plays a key role in maintaining the normal function of the intervertebral disc (IVD) by acting as a bridge for the transport of nutrients into the IVD cells. In this study, we developed a 3D dual inversion recovery prepared ultrashort echo time (DIR-UTE) sequence for high contrast CEP imaging and compared its performance with previously developed techniques on a clinical 3T scanner. We found that the proposed DIR-UTE sequence demonstrated the best image contrast for CEP imaging, which is highly promising for future clinical use.

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