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Abstract #1112

Rapid Isotropic 3D T2 Mapping of the Knee using Dual-Echo Steady-State MRI with Compressed Sensing Reconstruction

Shu-Fu Shih1,2, Zhaohuan Zhang1,2, Ashmita Deb1,2, Xiaodong Zhong3, Timothy W. Ryan1, and Holden H. Wu1,2
1Radiological Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, United States, 2Bioengineering, University of California Los Angeles, Los Angeles, CA, United States, 3MR R&D Collaborations, Siemens Medical Solutions USA, Inc., Los Angeles, CA, United States

Synopsis

Keywords: Cartilage, Cartilage

MRI T2 mapping of cartilage has been shown to be useful in characterization and monitoring of osteoarthritis (OA). Compared to conventional spin echo-based sequences, the 3D dual-echo steady-state (DESS) sequence can provide faster T2 mapping. Previous works proposed 3D DESS T2 mapping in the knee using anisotropic resolution (e.g., in-plane resolution of 0.3x0.3mm2 and slice thickness of 1.5-3mm), which limits the depiction of fine structures in 3D multiplanar reformatted images. This work investigated 3D DESS T2 mapping in the knee with isotropic acquired resolution of 0.66x0.66x0.66 mm3 and used compressed sensing (CS) to accelerate the acquisition time to <5 minutes.

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