Abstract #1113

Patellofemoral cartilage compression and recovery in response to loading measured with dynamic MRI using prospective motion correction

Thomas Lange¹, Philipp Rovedo¹, Patrick Hucker¹, Elham Taghizadeh^2,3, Kaywan Izadpanah⁴, Maxim Zaitsev¹, and Hans Meine^2,3

¹Division of Medical Physics, Department of Diagnostic and Interventional Radiology, Medical Center - University of Freiburg, Freiburg, Germany, ²Fraunhofer Institute for Digital Medicine MEVIS, Bremen, Germany, ³Medical Image Computing Group, Department of Informatics, University of Bremen, Bremen, Germany, ⁴Department of Orthopedic and Trauma Surgery, Medical Center – University of Freiburg, Freiburg, Germany

Synopsis

Keywords: Cartilage, Motion Correction, dynamic MRI, loading, compression, recoveryThe patellofemoral cartilage compression and recovery is measured with dynamic MRI in response to a bout of in situ loading in a cohort of ten healthy subjects. To mitigate motion artifacts arising from the loading paradigm, the experiments are performed with prospective motion correction based on optical tracking. The measured cartilage compression and recovery time course in response to loading and unloading is characterized by a larger fully elastic compression component adapting instantaneously to applied load changes, and a smaller compression component, which only gradually adapts to load changes and exhibits in particular a very protracted recovery after unloading.

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