Keywords: Pulse Sequence Design, Diffusion/other diffusion imaging techniques, abdomen, free-breathingAbdominal imaging is frequently performed with uncomfortable breath holds, or respiratory triggering to reduce the effects of respiratory motion. Diffusion weighted sequences provide a useful clinical contrast but have prolonged scan times due to low SNR. These scans cannot be reliably completed in a single breath hold, and respiratory triggering has low scan efficiency. We present a respiratory resolved, diffusion-prepared 3D sequence that obtains distortionless diffusion weighted images during free-breathing. We describe techniques to address the myriad of challenges including: 3D shot-to-shot phase correction, respiratory binning, diffusion encoding during free-breathing, and robustness to off-resonance.
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