Abstract #1179

Advances in Post-Perfusion Venous Territories Imaging with Displacement Spectrum Imaging (DiSpect)

Ekin Karasan¹, Jingjia Chen¹, Julian Maravilla¹, Zhiyong Zhang², Chunlei Liu^1,3, and Michael Lustig¹

¹Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, United States, ²School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, ³Helen Wills Neuroscience Institute, Berkeley, CA, United States

Synopsis

Keywords: Pulse Sequence Design, PerfusionDiSpect resolves the multi-dimensional displacement spectrum that spins exhibit between tagging and imaging. Previously, we showed that DiSpect can be used to trace blood draining from the capillary bed through the cerebral venous system. This work presents three innovations: 1) Validation of our results with flow phantom experiments and comparison of our in-vivo data with a detailed QSM-venogram. 2) Interleaved imaging to simultaneously probe the deep and superficial veins. 3) Use of a conformal head-cap array for imaging, with higher SNR, allowing dynamic measurement of vein drainage and observation of venous territories across large time scales.

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