Abstract #1187

Effects of free breathing on cerebrospinal fluid hydrodynamics: a study based on real-time phase-contrast MRI

Pan LIU^1,2, Kimi Piedad Owashi¹, Heimiri Monnier¹, Serge Metanbou³, Cyrille Capel⁴, and Olivier Balédent^1,2

¹CHIMERE UR 7516, Jules Verne University of Picardy, Amiens, France, ²Medical Image Processing Department, Amiens Picardy University Hospital, Amiens, France, ³Radiology Department, Amiens Picardy University Hospital, Amiens, France, ⁴Neurosurgery Department, Amiens Picardy University Hospital, Amiens, France

Synopsis

Keywords: Neurofluids, Neurofluids, breathing effects, cerebrospinal fluid, real time phase contrastThe effect of breathing on CSF is not well understood. Real-time phase-contrast MRI can quantify CSF flow continuously. A time-domain multi-parameter analysis method was developed to quantify the effect of free breathing on CSF. It was found that the cardiac period and the average stroke volume of CSF at second-to-third cervical vertebrae level and at the aqueduct were significantly increased during the expiratory phase, while the net flow of CSF was notably decreased.

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