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Abstract #1191

Magnetization transfer imaging of patients with Guillain-Barre Syndrome

Alison R Roth1 and Richard D Dortch2
1Barrow Neuroimaging Innovation Center, Barrow Neurological Institute, Phoenix, AZ, United States, 2Barrow Neurological Institute, Phoenix, AZ, United States

Synopsis

Keywords: Nerves, Magnetization transfer, Guillain-Barre SyndromeNew biomarkers are needed in Guillain-Barre Syndrome to predict patient recovery and severe complications and aid in drug development. We propose using magnetization transfer (MT) MRI to measure myelin content to act as such a biomarker. We have shown the ability of the MT imaging to visualize the cauda equina, but further work is needed to confirm these differences and biomarker suitability.

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