Abstract #1193

Pathogenesis of Chiari Malformation:insights from morphology,neurobiology and hydrodynamics based on MR neuroimaging technology

Yishuang Wang¹, Yun sen HE², Meining Chen³, Yuting Wang¹, and Longlin Yin¹

¹Radiology, Sichuan Provincial People's Hospital, Chengdu, China, ²Department of Neurosurgery, Sichuan Provincial People's Hospital, Chengdu, China, ³MR Scientific Marketing, Siemens Healthcare, Shanghai, China

Synopsis

Keywords: Nerves, NervesThe pathogenic mechanism of different clinical and radiologic manifestations of Chiari malformation I (CMI) is still unclear. Using MR morphology, neurobiology, and hydrodynamics techniques allow for a comprehensive assessment of CMI. FA values and CSF flow may well explain the correlation between white matter fiber tract, CMI pain, and compensations at other body parts. MRI technology helps us to better understand the pathogenic mechanism of CMI and can provide more valuable information in the diagnosis and treatment of CMI.

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