Abstract #1215

Dynamic glucose-enhanced imaging of the liver using breath-hold black blood quantitative T1rho MRI

Yurui Qian¹, Vincent Wai-Sun Wong², Jian Hou¹, Baiyan Jiang^1,3, Xinrong Zhang², Grace Lai-Hung Wong², Zhigang Wu⁴, Queenie Chan⁵, Simon Chun Ho Yu¹, Winnie Chiu-Wing Chu¹, and Weitian Chen¹

¹Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ²Medical Data Analytics Centre (MDAC), Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ³Illuminatio Medical Technology Limited, Hong Kong, Hong Kong, ⁴Philips Healthcare, Shenzhen, China, ⁵Philips Healthcare, Hong Kong, Hong Kong

Synopsis

Keywords: Liver, LiverNon-alcoholic fatty liver disease (NAFLD) is often associated with abnormal metabolic syndrome. In this study, we investigated dynamic glucose enhanced imaging of the liver using T1rho MRI after glucose ingestion. We hypothesize this approach can be used to assess metabolic activities in the liver. Sixteen young volunteers and four patients with NAFLD were recruited in this study. The preliminary results suggest that the proposed approach has the potential to detect metabolic variations between normal subjects and subjects with fatty liver.

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