Abstract #1218

Predicting microvascular invasion of HCC using whole-lesion histogram analysis with the interstitial fluid pressure and velocity model

Liyun Zheng^1,2,3, Chun Yang^1,2, Yongming Dai⁴, and Mengsu Zeng^1,2

¹Shanghai Institute of Medical Imaging, Shanghai, China, ²Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China, ³Shenzhen United Imaging Research Institute of Innovative Medical Equipment, Shenzhen, China, ⁴MR Collaboration, Central Research Institute, United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Liver, LiverMost solid tumors have increased interstitial fluid pressure (IFP), and the increased IFP is an obstacle to treatment. This study applied a non-invasive dynamic contrast-enhanced magnetic resonance imaging-based model to acquire IFP and interstitial fluid velocity (IFV). Based on the IFP and IFV maps, histogram analysis was applied to evaluate the spatial distributions of pixel gray levels with reduced sampling bias. IFP- and IFV-derived parameters have proven to be significant predictors of microvascular invasion status. Therefore, this optimal model, together with histogram analysis, offers a new way for in vivo and non-invasive assessment of hepatocellular carcinoma.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.