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Abstract #1222

The value of amide proton-weighted imaging and diffusion kurtosis imaging in predicting Her-2 expression in endometrial cancer

Xiwei Li1, Shifeng Tian1, Changjun Ma1, Nan Wang1, Jiazheng Wang2, and Ailian Liu1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Philips Healthcare,Beijing, Beijing, China

Synopsis

Keywords: Cancer, BodyEndometrial cancer (EC) is one of the three major malignant tumors in women, and its commonly used treatment is mainly surgery, radiotherapy, chemotherapy and hormone therapy . However, some patients still have low response to the above treatments. However, molecular therapy targeting Her-2 gene has significant value in the clinical diagnosis and improving the prognosis. Amide proton weighted imaging (APTw) and diffusion kurtosis imaging (DKI)can be used for the diagnosis of diseases by reflecting the level of molecular metabolism and cellular microstructure. This study explored the value of the above two sequences in quantitative prediction of HER-2 gene expression levels.

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Keywords