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Abstract #1223

Probing Possible Composition Changes of Placenta over Gestation Age Using Diffusion‐Relaxometry Correlated Spectroscopy Imaging

Xilong Liu1, Chantao Huang1, Wentao Hu2, Jie Feng1, Wenjun Qiao1, Sijin Chen1, Bo Liu1, Yongming Dai2, and Yikai Xu1
1Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 2MR Collaboration, Central Research Institute, United Imaging Healthcare, Shanghai, China

Synopsis

Keywords: Placenta, Diffusion/other diffusion imaging techniquesCurrently, antenatal noninvasive imaging techniques to directly evaluate placental function remains challenge. The objective of this study was using diffusion-relaxometry correlated spectrum imaging (DR-CSI) as a tool to probe the possible placental composition changes over gestation in normal pregnancy. Four to five peaks were visible in the D-T2 spectrum for most subjects. DR-CSI compartments were defined according to peak distribution. Significant correlation between DR-CSI compartment volume fractions and GA was found. We suggested that the DR-CSI technique could be used to reveal features of placental composition.

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Keywords