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Abstract #1243

4D flow MRI for investigation of fetal cardiovascular hemodynamics in healthy development and ductal dependent lesions

Erin K Englund1, Takashi Fujiwara1, Sarah Smith2, Bettina Cuneo3, Mehdi Hedjazi Moghari1, Mariana L Meyers1, Richard M Friesen3, Lorna P Browne1, and Alex J Barker1
1Radiology, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States, 2Radiology, Children's Hospital Colorado, Aurora, CO, United States, 3Pediatric Cardiology, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States

Synopsis

Keywords: Fetal, Velocity & FlowFetal cardiovascular MRI has the potential to aid in the diagnosis and evaluation of congenital heart disease. Here, a fast, Doppler ultrasound- gated, 4D flow MRI acquisition with online reconstruction was achieved in twelve healthy fetuses and six patients with suspected congenital cardiovascular defects. Analysis of the 4D flow data revealed expected flow distributions across vascular territories in the healthy cohort. Using 4D flow MRI, we were also able to evaluate the presence and impact of ductal dependent lesions in patients with suspected congenital heart disease, finding confirmation of presence/absence of pathology on post-natal imaging.

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Keywords