Meeting Banner
Abstract #1254

In-vivo T1 mapping for quantitative evaluation of intracranial atherosclerotic plaques

Jiaqi Dou1, Xiaoming Liu2,3, Yajie Wang1, Ziming Xu1, Jing Wang2,3, and Huijun Chen1
1Center for Biomedical Imaging Research, Tsinghua University, Beijing, China, 2Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 3Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China

Synopsis

Keywords: Quantitative Imaging, AtherosclerosisT1 mapping could provide more reliable quantitative measurements of plaques than traditional T1w MR images. In this study, the feasibility of in vivo quantitative T1 mapping of intracranial plaque had been demonstrated for the first time using a 3D SNAP with golden angle radial k-space sampling (GOAL-SNAP) sequence. Symptomatic patients showed significantly lower intraplaque T1 values than asymptomatic patients (1695.21 ± 493.23 vs. 2241.76 ± 300.28 ms, p=0.045). Quantifying plaque T1 values and enhancement through 3D GOAL-SNAP T1 mapping images is promising for characterizing the symptomatic plaques, serving as one potential tool for further plaque analysis.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords