Meeting Banner
Abstract #1259

Histological Validation of MR Cell Size and Cellularity Imaging with Human Liver Specimens

xiaoyu jiang1, John Gore2, and Junzhong Xu3
1Radiology, Vanderbilt University Medical Center, nashville, TN, United States, 2Vanderbilt University Medical Center, nashville, TN, United States, 3Vanderbilt University Medical Center, Brentwood, TN, United States

Synopsis

Keywords: Quantitative Imaging, Liver, microstructure; diffusion; inflammationThe size and cellularity of hepatocytes, their variations and changes over time, are fundamental characteristics of liver tissues, and measurements of cell sizes and cellularities may have high clinical significance but currently can be obtained only by liver biopsy. We quantified the microstructures of human liver specimens with different liver diseases, including normal liver tissues, cirrhosis, steatosis, hepatocellular carcinoma (HCC), cirrhotic regenerative nodules (CRN), and intrahepatic cholangiocarcinoma (iCCA), using MR cell size imaging ex vivo. The accuracy of MR-derived cell sizes and cellularities were evaluated by comparisons to histology.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords