Abstract #1262

Evaluation of Activity of Graves’ Orbitopathy by Multiparameter Orbital MRI

Xinyi Gou¹, Xiuying Zhang², Jianxiu Lian³, Xiaofang Xu³, Zhenyu Piao⁴, Lingli Zhou², Jingyi Cheng¹, Chuhan Chen¹, Lei Chen¹, Ke Jiang³, Jin Cheng¹, Linong Ji², and Nan Hong¹

¹Department of Radiology, Peking University People’s Hospital, Beijing, China, ²Department of Endocrinology, Peking University People’s Hospital, Beijing, China, ³Philips Healthcare, Beijing, China, ⁴Department of Ophthalmology, Peking University People’s Hospital, Beijing, China

Synopsis

Keywords: Quantitative Imaging, MR ValueThe evaluation in activity of Graves’ orbitopathy (GO) has important clinical significance for the treatment decision making and prognosis prediction for GO patients. Some previous studies have a limited comprehensive consideration that GO could involve almost entire orbital region, leading to complex changes in MR quantitative parameter, such as T1, T2, and fat fractions. In this study, we established a combined model including MRI quantitative parameters concerning multiple tissues of eyes and multiple sequences to distinguish active GO. And it was better than using a certain parameter alone to evaluate GO activity.

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