Abstract #1270

Impact of EPI readout duration on the diffusion-fMRI response onset time

Shota Hodono¹, Jonathan R Polimeni^2,3, and Martijn A Cloos¹

¹Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ³Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

Synopsis

Keywords: fMRI (task based), Diffusion/other diffusion imaging techniquesWe investigated the impact of the EPI readout duration on the onset time of activation observed with diffusion functional MRI (DfMRI). Both long (28.5-ms) and short (12.5-ms) readouts showed a clear functional response, even in individual subjects. However, using a long readout the onset time was shifted towards SE-BOLD (1.6-s [short readout] vs 1.2-s [long readout]), suggesting that longer readouts make the DfMRI signal more similar to SE-BOLD, presumably due to increased BOLD contamination.

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