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Abstract #1276

Unlocking 20-fold acceleration towards 0.5-second whole-brain HCP-style fMRI

Omer Burak Demirel1,2, Luca Vizioli2,3, Burhaneddin Yaman1,2, Steen Moeller2, Logan Dowdle2,3, Essa Yacoub2, Kamil Ugurbil2, and Mehmet Akçakaya1,2
1Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Department of Neurosurgery, University of Minnesota, Minneapolis, MN, United States

Synopsis

Keywords: fMRI, fMRIFunctional MRI (fMRI) is acquired with simultaneous multi-slice (SMS) imaging and in-plane acceleration to provide sufficient coverage and spatio-temporal resolutions. However, further accelerations are desirable to achieve BRAIN initiative targets. In this work, we investigate self-supervised deep learning reconstruction at 20-fold (SMS×in-plane=5×4) retrospective and prospective accelerations. Results show DL at 20-fold retrospective acceleration is similar to split slice-GRAPPA at 10-fold acceleration. Furthermore, we show that DL method trained on retrospective 20-fold acceleration generalizes well and successfully reconstructs prospectively 20-fold accelerated fMRI data.

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Keywords