Keywords: fMRI (task based), Preclinical, Implantable CoilThis study utilizes implantable RF coils affixed to mouse heads which are used as head fixation points to minimize motion and remove B1-related artifacts due to motion-induced loading change during scanning. This method increases SNR significantly and enables high-resolution EPI-based functional imaging in awake mice at 14T, highlighting both cortical and subcortical activation following visual and whisker stimulation. Furthermore, this high-resolution awake mouse fMRI setup enables high sensitivity to map brain activation from subcortical nuclei and extends the detection of associated brain regions related to the stimulation.
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